翻訳と辞書 Words near each other ・ Phosphoryl group ・ Phosphoglycolate phosphatase ・ Phosphogypsum ・ Phosphohydroxypyruvic acid ・ Phosphoinositide 3-kinase ・ Phosphoinositide 3-kinase inhibitor ・ Phosphoinositide 5-phosphatase ・ Phosphoinositide phospholipase C ・ Phosphoinositide-dependent kinase-1 ・ Phosphoketolase ・ Phospholamban ・ Phosphole ・ Phospholipase ・ Phospholipase A ・ Phospholipase A1 ・ Phospholipase A2 ・ Phospholipase B ・ Phospholipase C ・ Phospholipase D ・ Phospholipase D1 ・ Phospholipid ・ Phospholipid acyltransferase ・ Phospholipid scramblase ・ Phospholipid transfer protein ・ Phospholipid-derived fatty acids ・ Phospholipid-hydroperoxide glutathione peroxidase ・ Phospholipid-translocating ATPase ・ Phospholipidosis ・ Phosphomannan mannosephosphotransferase ・ Phosphomannomutase Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Phospholipase A2 ： ウィキペディア英語版 Phospholipase A2 Phospholipases A2 (PLA2s) are enzymes that release fatty acids from the second carbon group of glycerol. This particular phospholipase specifically recognizes the sn-2 acyl bond of phospholipids and catalytically hydrolyzes the bond releasing arachidonic acid and lysophospholipids. Upon downstream modification by cyclooxygenases, arachidonic acid is modified into active compounds called eicosanoids. Eicosanoids include prostaglandins and leukotrienes, which are categorized as anti-inflammatory and inflammatory mediators. PLA2 are commonly found in mammalian tissues as well as insect and snake venom. Venom from both snakes and insects is largely composed of melittin, which is a stimulant of PLA2. Due to the increased presence and activity of PLA2 resulting from a snake or insect bite, arachidonic acid is released from the phospholipid membrane disproportionately. As a result, inflammation and pain occur at the site. There are also prokaryotic A2 phospholipases. Additional types of phospholipases include phospholipase A1, phospholipase B, phospholipase C, and phospholipase D. ==Families== Phospholipases A2 include several unrelated protein families with common enzymatic activity. Two most notable families are secreted and cytosolic phospholipases A2. Other families include Ca2+ independent PLA2 (iPLA2) and lipoprotein-associated PLA2s (lp-PLA2), also known as platelet activating factor acetylhydrolase (PAF-AH). 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Phospholipase A2」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.